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Table 10 Predicted genes for gap-filling SMILEY solutions

From: Gap-filling analysis of the iJO1366 Escherichia coli metabolic network reconstruction for discovery of metabolic functions

Hypothesized changes in directionality

 

Reaction

Support

 

DOGULNR

not reversible (EcoCyc)

 

DKGLCNR1

reversible (Habrych et al. [41])

DKGLCNR2y

reversible (Yum et al. [42])

PGLYCP

not reversible (EcoCyc)

 

CYSSADS

  

HMPK1

not reversible (EcoCyc)

 

4HTHRS

  

HETZK

not reversible (EcoCyc)

 

NNDMBRT

not reversible (EcoCyc)

 

ACONMT

not reversible (EcoCyc)

 

CINNDO

not reversible (EcoCyc)

 

MCPST

  

GPDDAS

not reversible (EcoCyc)

 

APCS

not reversible (EcoCyc)

 

SARCOX

  

Hypothesized gap-filling reactions

 

Reaction

Putative gene

E-value

R01742 (F)

ydiS (b1699)

0.003

R00893 (F)

ygfM (b0419)

0.58

R02133 (F)

yhbO (b3153)

0.069

R02721 (F)

global orphan

 

R03472 (R)

global orphan

 

R01297 (R)

global orphan

 

R01299 (R)

global orphan

 

R02252 (F)

fadH (b3081)

7.00E-71

 

nemA (b1650)

1.00E-22

R00895 (R)

aspC (b0928)*

 

R03530 (F)

ndk (bb2518)*

 

R00012 (F)

global orphan

 

R01232 (R)

yjhG (b4297)

0.028

 

yagF (b0269)

0.057

R00838 (F)

chbF (b1734)

9.00E-42

 

melA (b4119)

2.00E-21

R00655 (R)

global orphan

 

R07300 (F)

global orphan

 

R00683 (F)

global orphan

 

R00367 (F)

global orphan

 

R02559 (F)

global orphan

 

R02560 (F)

global orphan

 

R05623 (F)

yjiN (b4336)

0.16