Table 2 Top 10 miRNAs and TFs with highest out-degree in lung cancer synergistic regulatory network

1

hsa-miR-590-3p

320

-

2

hsa-miR-548c-3p

302

-

3

hsa-miR-570

243

-

4

hsa-miR-340

242

-

5

hsa-miR-495

218

-

6

hsa-miR-106a^b

207

PMID: 19209007

7

hsa-miR-106b^b

202

-

8

hsa-miR-20a^b

201

PMID: 16266980

9

hsa-miR-20b^b

200

-

10

hsa-miR-944

200

-

1

MYC

116

PMID: 11720740

2

TP53

95

PMID: 12619108

3

E2F1

73

PMID: 22803943

4

TFAP2A

64

PMID: 22143938

5

SP1

61

PMID: 22158040

6

JUN

59

-

7

E2F4

50

PMID: 19473719

8

HIF1A

48

PMID: 22115707

9

NFKB1

48

-

10

STAT1

44

PMID: 17348819