A network-based approach for predicting key enzymes explaining metabolite abundance alterations in a disease phenotype

Table 1 Details of 4 top-ranked reactions responsible for the accumulation of LCystin

Reaction names	∆L_j	p-value
Cysteine oxidase	0.700348	0.0060
Formaldehyde dehydrogenase	0.637731	0.0190
S-formylglutathione hydralase	0.637731	0.0190
Sulfite oxidase	0.636891	0.0060

ISSN: 1752-0509