A network-based approach for predicting key enzymes explaining metabolite abundance alterations in a disease phenotype

Table 2 Details of 4 top-ranked reactions responsible for the accumulation of HCys

Reaction names	∆L_j	p-values
Phosphatidylethanolamine N-methyltransferase	0.768421	0.0010
S-Adenosyl-L-methionine reversible transport, mitochondrial	0.768421	0.0010
Phosphatidylserine decarboxylase	0.767333	0.0130
Phosphatidylserine flippase	0.767333	0.0130

ISSN: 1752-0509