From: SignaLink 2 – a signaling pathway resource with multi-layered regulatory networks
KEGG[71] | Reactome[72] | SPIKE[73] | ConsensusPathDB[74] | TranscriptomeBrowser[10] | SignaLink 1[1] | SignaLink 2 | |
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Model species # | √ | √ | √ | ||||
Containsmanual curation § | √ | √ | √ | √ | √ | ||
Contains integrated data | √ | √ | √ | ||||
Reference for each interaction | √ | √ | √ | √ | |||
Cross-talks and multi-pathway proteins * | √ | √ | √ | ||||
Undirected protein-protein interactions | √ | √ | √ | √ | √ | ||
Directed protein-protein interactions † | √ | √ | |||||
Transcription factor regulation | √ | √ | √ | √ | |||
miRNA regulation | √ | √ | |||||
Transcription factors that regulate miRNAs | √ | ||||||
Confidence score for the interactions | √ | ||||||
Customizable download options | √ˣ | √ | √ | ||||
Freely downloadable for academic users | √ | √ | √ | √ | √ | √ |