Figure 4
From: Global dynamic optimization approach to predict activation in metabolic pathways
Glycolysis inspired network with two outputs. A) Schematic representation of the branched pathway with two outputs (S 5 and S 6). B) Pareto front obtained for the maximization of both products of a branched pathway (S 5 and S 6) using Equation (32). C) Optimal enzyme profiles for the maximization of the two different outputs of a pathway (P 1, P 2 and P 3). Control variables have been approximated using ρ=120 steps with fixed duration. Enzyme and metabolite concentrations are expressed in concentration units (mM) and time in seconds (s).