Figure 3

The static and dynamic examples where the truth is known. (A) The static model structures, where x and f(x) are the input and measured output, respectively, and where the θ s are unknown parameters to be estimated from the data. (B) Vertical lines are data points (mean plus/minus standard deviation) from an example of a bootstrap from the model structure${\mathcal{M}}_{S1}$, and the green and blue lines are corresponding fits from the two model structures. (C) The two dynamic model structures, involving a decay of the substrate X ₁, which occurs via mass action or Michaelis-Menten kinetics, respectively. (D) Vertical lines are data points (mean plus/minus standard deviation) from a bootstrap generated by${\mathcal{M}}_{D2}$, and the blue and green lines are corresponding model fits by the two model structures. Equations and details regarding fits etc. are found in Materials and Methods.