Figure 1From: Integrative analysis of differential miRNA and functional study of miR-21 by seed-targeting inhibition in multiple myeloma cells in response to berberine Ingenuity analysis of miRNA predictive pathways. Among the 49 down-regulated miRNAs, 28 were shown by mirFocus to be involved in p53 signaling, cell cycle and other cancer pathways. miR-21 participates in all the above signaling pathways, and can be considered as one of the most important oncomirs in the effects of BB on MM.Back to article page