Figure 2

Feature analysis on protein 1AKHchain A. (A) The discriminant weights of the 400 amino acid pairs. Each element in the figure refers to the quadratic sum of the discriminant weights of descriptors with positive discriminant weight for a certain amino acid pair. A amino acid pair is identified by two amino acids, the x-axis and y-axis represent its second amino acid and first amino acid, respectively. (B) The discriminant weights of the descriptors with different lg values for the top four most discriminant amino acid pairs, including pair(R,R), pair(R,P), pair(P,R) and pair(A,R). (C) The occurrence distributions of the descriptors for the top four most discriminant amino acid pairs on the DNA-binding regions and non DNA-binding regions of protein 1AKH chain A, respectively. The regions in green color are non DNA-binding regions and the region in grey color is DNA-binding protein. (D) The occurrence distributions of the descriptors for the top four most discriminant amino acid pairs on the three dimensional structure of protein 1AKH chain A. The green sections are the three dimensional structure of protein and the brown sections are the three dimensional structure of the DNA.