Identification of network-based biomarkers of cardioembolic stroke using a systems biology approach with time series data

Table 2 Top proteins at 3 time points post-stroke/

Protein	SRV	pvalue	Case_AvgExp	Control_AvgExp	Log2FC
5 proteins at 3 h post-stroke
UBC [36]	6.07	<10^-9	18100	19375	-0.1
CUL3 [37]	3.26	0.001157	4178	3592	0.22
RNF2 [38]	1.77	0.031488	19	18	0.06
ATXN2L [39]	1.68	0.037603	70	164	-1.23
TTN [40]	1.65	0.041157	371	139	1.42
9 proteins at 5 h post-stroke
UBC	11.69	<10^-9	18178	19375	-0.09
APP [41]	5	3.24E-05	1651	2018	-0.29
CUL3	4.44	0.000421	4486	3592	0.32
NEDD8 [42]	2.69	0.010615	3413	2952	0.21
PAN2 [43]	2.62	0.012395	293	491	-0.74
ELAVL1 [44]	2.53	0.014757	825	800	0.04
DBN1 [45]	2.37	0.021003	261	128	1.03
TCOF1 [46]	2.09	0.039515	109	229	-1.08
JUP [47]	2.06	0.042265	8	32	-2.04
4 proteins at 24 h post-stroke
UBC	25.99	<10^-9	17540	19375	-0.14
APP	5.06	<10^-9	1653	2018	-0.29
CUL3	2.82	0.003012	4554	3592	0.34
SIRT7 [48]	1.66	0.042587	720	594	0.28

ISSN: 1752-0509