Figure 4From: The role of TGF-β signaling and apoptosis in innate and adaptive immunity in zebrafish: a systems biology approach Interactions of Acvr1b with other proteins in secondary infection. Acvr1b, Smad2 and Smad3 were found to be important in secondary infection. Smad7, an inhibitory SMAD protein, interacted with Acvr1b in secondary but not primary infection. This disparity suggests that TGF-β signaling may play a role in the control of innate and adaptive immune responses.Back to article page