Table 4 Zebrafish proteins identified to have the most significant changes in the number of PPI linkages between primary and secondary C. albicans infection

1

Psmd13

5

12

17

Adaptive immunity

[16]

2

Psmd1

6

11

17

Adaptive immunity

[16]

3

Casp2

5

11

16

Apoptosis

[17]

4

Ncstn

5

11

16

Immune recognition

[18]

5

Wdr82

6

10

16

Unknown

6

Fos

3

9

12

Innate immunity

7

Acvr1b

1

8

9

Induction of apoptosis

[19]

Activation of mast cells

[20]

Regulation of immunoglobulin

[21]

8

Ampste24

4

4

8

Unknown

9

Loc553343

3

4

7

Unknown

10

Hsp90a.1

2

4

6

Apoptosis

[22],[23]

Antigen presentation

[24]