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Fig. 6 | BMC Systems Biology

Fig. 6

From: Tip cell overtaking occurs as a side effect of sprouting in computational models of angiogenesis

Fig. 6

Leader cell identification. Schematic representation of a sprout to illustrate the identification of the leader cell. Line e is drawn through nodes B and E to find T, the furthest lattice site in the sprout on line e. Line a is perpendicular to line e and through T. The cell in which E is located and its neighbors that are on line a, are candidates to become the leader cell. The cell with the lattice site farthest from B (indicated with a star) and is connected to B through at least an equal amount of cells, will become the leader cell (indicated in red)

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