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Fig. 4 | BMC Systems Biology

Fig. 4

From: Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion

Fig. 4

Enrichment of DEGs in a region of chromosome 6 predicted to interact with 22q11.2. Scatterplot presenting the –log10 (p-values) (y-axis) of changes in gene expression for each gene along chromosome 6. The heat map below shows the reported Hi-C correlation between each section of chromosome 6 and the 22q11.2 region. Note that the 6p21 region, which is highlighted by a yellow box in the heat map, was enriched for differentially expressed genes, and it displayed the strongest physical interaction with 22q11.2

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BMC Systems Biology

ISSN: 1752-0509

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