Network reconstruction of the mouse secretory pathway applied on CHO cell transcriptome data

BMC Systems Biology

Table 2 Overview of culture condition at RNA sampling

#	Cell line	Condition^a	μ [h⁻¹]	t_d [h]	q_IgG	Time [h]
1.1	CHO-K1	Exponential phase	0.0353	19.6	0	24
1.2	CHO-K1	Stationary phase	0.001	693.1	0	120
2.1.1	CHO DG44 IgG	Exponential phase	0.0231	30.0	9.93	48
2.1.2	CHO DG44 IgG	Stationary phase	0.0008	866.4	8.28	140
2.2.1	CHO DG44 IgG	Exponential phase, 0% NEAA	0.0235	29.5	8.46	48
2.2.2	CHO DG44 IgG	Stationary phase, 0% NEAA	0.0094	73.7	8.42	130
2.3.1	CHO DG44 IgG	Secretory stress by NaBu	0	−99.0	11.86	70
2.3.2	CHO DG44 IgG	Secretory stress by NaBu	0	−138.6	17.12	100

^aCondition at the time point of RNA sampling, μ: Specific growth rate, t_d: Doubling time, q_IgG: Specific IgG production rate, Time: Time of cultivation

ISSN: 1752-0509