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Figure 4 | BMC Systems Biology

Figure 4

From: An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline

Figure 4

Model parameters that affect protein half-life. Results are shown for a typical simulation, for a 12 hour period. Protein synthesis was blocked by setting k1 = 0 with all other parameters as in Tables 2 and 3 except where indicated. The curves show the decline in total protein with time. The half-life is the time when the total protein level is equal to 250.

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