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Table 1 Parameters used in model of the EBV genetic switch

From: Epstein-Barr virus latency switch in human B-cells: a physico-chemical model

Name Value Reference
K dE * 1 nM (0.1 – 10 nM) Assumed model parameter
K dEFR 15 pM [39]
K dOFR * 2.5 nM (2.5 – 12.5 nM) [41]
K dQ 0.21 μ M [39]
E tot in lat III 34,000 molecules [43]
τ 1/2 48 h [44,45]
cell division time 24 h [46]
Nucleus volume * 2e -13 l(2e -14 - 2e -12 l) [48]
  1. Each Paramater is presented with a name, also used in the Methods section, and its value and corresponding reference puplication. *The three parameters that were altered in robustness tests. The range is given in Parenthesis.