Table 5 Major hubs of the comprehensive lactation network

21

[PIR:P00533]/EGFR

Epidermal growth factor receptor precursor

17

[PIR:P04181]/OAT

Ornithine aminotransferase, mitochondrial

14

[PIR:P35520]/CBS

Cystathionine beta-synthase

13

[PIR:O60674]/JAK2

Tyrosine-protein kinase JAK2

12

[PIR:P04626]/ERBB2

Receptor tyrosine-protein kinase erbB-2 precursor

12

[PIR:P40763]/STAT3

Signal transducer and activator of transcription 3

12

[PIR:P36543]/ATP6V1E1

Vacuolar ATP synthase subunit E

11

[PIR:P38398]/BRCA1

Breast cancer type 1 susceptibility protein

11

[PIR:P42229]/STAT5A

Signal transducer and activator of transcription 5A

11

[PIR:P52209]/PGD

6-phosphogluconate dehydrogenase, decarboxylating

11

[PIR:Q00341]/HDLBP

Vigilin

11

[PIR:P35606]/COPB2

Coatomer subunit beta

10

[PIR:P10912]/GHR

Growth hormone receptor precursor

10

[PIR:P29350]/PTPN6

Tyrosine-protein phosphatase non-receptor type 6

10

[PIR:P06730]/EIF4E

Eukaryotic translation initiation factor 4E

10

[PIR:P49591]/SARS

Seryl-tRNA synthetase, cytoplasmic

10

[PIR:Q15437]/SEC23B

Protein transport protein Sec23B

10

[PIR:O14929]/HAT1

Histone acetyltransferase type B catalytic subunit

9

[PIR:O14543]/SOCS3

Suppressor of cytokine signaling 3

9

[PIR:P35568]/IRS1

Insulin receptor substrate 1

9

[PIR:O15524]/SOCS1

Suppressor of cytokine signaling 1

9

[PIR:Q15796]/SMAD2

Mothers against decapentaplegic homolog 2

9

[PIR:P61960]/UFM1

Ubiquitin-fold modifier 1 precursor

8

[PIR:P06213]/INSR

Insulin receptor precursor

8

[PIR:O75821]/EIF3S4

Eukaryotic translation initiation factor 3 subunit 4

8

[PIR:P17676]/CEBPB

CCAAT/enhancer-binding protein beta

8

[PIR:P04150]/NR3C1

Glucocorticoid receptor