Clustering-coefficient profiles for the TF-projected networks under directed attacks to the best connected transcription factors and regulated genes. In these panels, we show the average clustering coefficient value of TF-projected networks after attacks according to the color scheme shown in the bar. a) E. coli original network. b) S. cerevisiae original network. c) E. coli randomized network. d) S. cerevisiae randomized network. We remark the slightly slower decay of the clustering coefficient in the randomized case of E. coli TF network. For S. cerevisiae network no appreciable differences are observed between the original and randomized cases.