Three factors underlying incorrect in silico predictions of essential metabolic genes

BMC Systems Biology

Table 3 The fraction of blocked and completely blocked genes, both FN and non-FN.

Organism	Media	Fraction of non-FN genes blocked	Fraction of FN genes blocked	Fraction of non-FN genes completely blocked	Fraction of FN genes completely blocked
E. coli	glucose MM	0.36	0.37	0.09	0.10
	glycerol MM	0.38	0.37	0.10	0.08
S. cerevisiae	glucose	0.39	0.67	0.13	0.28
	glucose (anaerobic)	0.45	0.74	0.18	0.31
	galactose	0.37	0.64	0.14	0.21
	glycerol	0.38	0.64	0.14	0.25
	ethanol	0.37	0.71	0.13	0.28
	rich	0.39	0.69	0.13	0.29
H. pylori	rich	0.17	0.13	0.01	0
S. aureus	rich (Forsyth et al.)	0.39	0.56	0.13	0.19
	rich (Ji et al.)	0.39	1.00	0.13	0.6
M. tuberculosis	Middlebrook	0.29	0.40	0.07	0.07
B. subtilis	rich	0.43	0.19	0.12	0.17

ISSN: 1752-0509