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Table 2 Growth phenotypes of the core model. Consistent organizations in the core network model of the regulated central metabolism of E. coli, ordered by size.

From: Phenotype prediction in regulated metabolic networks

Consistent Organiza. Species Growth medium Uptake
1 Input metabolites, ADP, PI, ArcA, Fnr, GalR, GalS, GlpR, LacI, Mlc, PykF, Ubiquitous proteins - -
2 Input metabolites, ADP, O2, O2xt, PI, GalR, GalS, GlpR, LacI, Mlc, PykF, Ubiquitous proteins O2 -
3 Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, LCTSxt, NADH, PI, PPI, UDPG, ArcA, Crr, FadR, Fnr, Food, GalP, GalR, GalS, GlpR, LacI, Pgk, PtsGHI, PykF, Ubiquitous proteins GLC GLC
4 Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, LCTSxt, NADH, O2, O2xt, PI, PPI, UDPG, ArcA, Crr, FadR, Fnr, Food, GalP, GlpR, Pgk, PtsGHI, PykF, Ubiquitous proteins GLC, LCTS GLC
5 Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, GLxt, LCTSxt, NADH, PI, PPI, UDPG, ArcA, Crr, FadR, Fnr, Food, GalP, GalR, GalS, LacI, Pgk, PtsGHI, PykF, Ubiquitous proteins GLC, GL GLC
6 Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, GLxt, LCTSxt, NADH, O2, O2xt, PI, PPI, UDPG, ArcA, Crr, FadR, Fnr, Food, GalP, Pgk, PtsGHI, PykF, Ubiquitous proteins GLC, GL, LCTS GLC
7 Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, NADH, PI, PPI, UDPG, Crr, FadR, Food, GalP, GalR, GalS, GlpR, LacI, Pgk, PtsGHI, PykF, Ubiquitous proteins GLC, O2 GLC
8 Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, NADH, O2, O2xt, PI, PPI, UDPG, Crr, FadR, Food, GalP, GlpR, Pgk, PtsGHI, PykF, Ubiquitous proteins GLC, LCTS, O2 GLC
9 Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, GLxt, NADH, PI, PPI, UDPG, Crr, FadR, Food, GalP, GalR, GalS, LacI, Pgk, PtsGHI, PykF, Ubiquitous proteins GLC, GL, O2 GLC
10 Input metabolites, Glycolysis metabolites, ADP, G1P, GLC, GLCxt, GLxt, NADH, O2, O2xt, PI, PPI, UDPG, Crr, FadR, Food, GalP, Pgk, PtsGHI, PykF, Ubiquitous proteins GLC, GL, LCTS, O2 GLC
11 Input metabolites, Glycolysis metabolites, ADP, G1P, GL, GL3P, GLxt, NADH, NADPH, O2, O2xt, PI, PPI, QH2, UDPG, ArcA, Crr, Fnr, Food, GalP, GalR, GalS, GlpABC, GlpF, GlpK, LacI, Mlc, Pgk, PtsGHI, PykF, Ubiquitous proteins GL GL
12 Input metabolites, Glycolysis metabolites, ADP, G1P, GL, GL3P, GLxt, NADH, NADPH, PI, PPI, QH2, UDPG, Crr, Food, GalP, GalR, GalS, GlpD, GlpF, GlpK, LacI, Mlc, Pgk, PtsGHI, PykF, Ubiquitous proteins GL, O2 GL
13 Input metabolites, Glycolysis metabolites, Lactose derivatives, ADP, G1P, GLC, LCTS, LCTSxt, NADH, PI, PPI, UDPG, ArcA, Crr, Fnr, Food, GalE, GalK, GalM, GalP, GalT, GlpR, LacY, LacZ, Mlc, Pgk, PtsGHI, PykF, Ubiquitous Proteins LCTS LCTS
14 Input metabolites, Glycolysis metabolites, Lactose derivatives, ADP, G1P, GLC, LCTS, LCTSxt, NADH, O2, O2xt, PI, PPI, UDPG, ArcA, Crr, Fnr, Food, GalE, GalK, GalM, GalP, GalT, LacY, LacZ, Mlc, Pgk, PtsGHI, PykF, Ubiquitous Proteins GL, LCTS LCTS
15 Input metabolites, Glycolysis metabolites, Lactose derivatives, ADP, G1P, GLC, GLxt, LCTS, LCTSxt, NADH, PI, PPI, UDPG, Crr, Food, GalE, GalK, GalM, GalP, GalT, GlpR, LacY, LacZ, Mlc, Pgk, PtsGHI, PykF, Ubiquitous proteins LCTS, O2 LCTS
16 Input metabolites, Glycolysis metabolites, Lactose derivatives, ADP, G1P, GLC, GLxt, LCTS, LCTSxt, NADH, O2, O2xt, PI, PPI, UDPG, Crr, Food, GalE, GalK, GalM, GalP, GalT, LacY, LacZ, Mlc, Pgk, PtsGHI, PykF, Ubiquitous Proteins GL, LCTS, O2 LCTS
  1. For brevity, pseudo species indicating the absence of a species are not listed. A list of abbrevations can be found in the Supplement. A species followed by 'xt' denotes its extra-cellular form. "Ubiquitous proteins" include the proteins that are considered ubiquitously present in the cell and therefore are not listed separately. They are: Eno, Fba, Fbp, GalU, GapA, Glk, GpmA, GpmB, GpsA, PfkA, PfkB, Pgi, Pgm, PykA, and TpiA. "Input metabolites" denotes the metabolites provided as input to the system: HEXT (external hydrogen), Q (Ubiquinone), ATP, UTP, NAD, and NADP. "Glycolysis metabolites" denotes the metabolites of the glycolysis: G6P, F6P, FDP, T3P2, T3P1, 13PDG, 3PG, 2PG, PEP, and PYR. "Lactose derivatives" denotes the derivatives of lactose in the central metabolism: GAL1P, GLAC, UDPGAL, bDGLAC, bDGLC.