Average fraction of dimerised phosphorylated STAT5 in the nucleus ( DpS
) (norm. units versus the total amount of Epo ( Epo
) provided during the transient stimulation. The system was analysed for transient stimulation with total amount of Epo Epo
∈ [10-8,106] units/ml. The solid black line is used to highlight the different values of DpSnc,trobtained for a total amount of Epo of one hundred units. In this case the average of the system response ranges between 0.05 and 0.17 normalised units. The dashed black line is used to highlight how in the interval of intense stimulation input signals with totally different properties (Epo
∈ [101,105] units/ml) produce output signal with identical average intensity DpSnc,tr.