Metabolic modelling of polyhydroxyalkanoate copolymers production by mixed microbial cultures

BMC Systems Biology

Table 3 Kinetic model

Reaction	Kinetics
R ₄ : Growth on Acetyl-CoA	$R_{4} = R_{4, \max} \cdot \frac{A c}{A c + K_{S}} \cdot \frac{N}{N + K_{N}}$
R ₅ : Growth on Propionyl-CoA	$R_{5} = R_{5, \max} \cdot \frac{\Pr o p}{\Pr o p + K_{S}} \cdot \frac{N}{N + K_{N}}$
R ₆ : Catabolism	$R_{6} = R_{6, \max} \cdot \frac{S}{S + K_{S}}$
R ₇ : Maintenance	$R_{7} = R_{7, \max} \cdot \frac{S}{S + K_{S}}$
R ₉ *: Acetyl-CoA Production**	$R_{9} = \max {R_{9, \max} \cdot \frac{S}{S + K_{S}} \cdot [1 - {(\frac{f_{P H A}}{f_{P H A, \max}})}^{α}], \frac{2}{3} \cdot R_{10}}$
R ₁₀ *: Propionyl-CoA Production**	$R_{10} = R_{10, \max} \cdot \frac{S}{S + K_{S}} \cdot [1 - {(\frac{f_{P H A}}{f_{P H A, \max}})}^{α}]$

ISSN: 1752-0509