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Table 5 Reaction rules for the considered example of EGFR dimerization.

From: Exact model reduction of combinatorial reaction networks

R(0, *)

+

EGF

⇋

R(EGF, *)

k1, k-1

R(0, *).R(0, *)

+

EGF

⇋

R(EGF, *).R(0, *)

2k2, k-2

R(EGF, *).R(0, *)

+

EGF

⇋

R(EGF, *).R(EGF, *)

k2, 2k-2

R(0, X1)

+

R(0, X1)

⇋

R(0, X1).R(0, X1)

k3, k-3

R(0, X1)

+

R(0, X2)

⇋

R(0, X1).R(0, X2)

2k3, k-3

R(EGF, X1)

+

R(0, X1)

⇋

R(EGF, X1).R(0, X1)

k4, k-4

R(EGF, X1)

+

R(0, X2)

⇋

R(EGF, X1).R(0, X2)

2k4, k-4

R(EGF, X1)

+

R(EGF, X1)

⇋

R(EGF, X1).R(EGF, X1)

k5, k-5

R(EGF, X1)

+

R(EGF, X2)

⇋

R(EGF, X1).R(EGF, X2)

2k5, k-5

R(*, 0)

  

⇋

R(*, P)

k6, k-6

R(*, 0).R(*, 0)

  

⇋

R(*, P).R(*, 0)

2k7, k-7

R(*, P).R(*, 0)

  

⇋

R(*, P).R(*, P)

k7, 2k-7

  1. Herein the identifiers X n also indicate that the related domains can be in various states as the identifier * does. However, all domains with the identifier X n within one rule have to be in the same state. If two different identifiers X i and X j occur within one rule the respective domains are not allowed to be in the same state.