Clustering of 100,000 simulated components from the two established clusters and structural location within skeletal muscle. 100,000 components were clustered into the two groups based on the resulting clustering criteria to better establish the boundary between clusters. The genes encoding the proteins belonging to the structural locations, including their paralogs have been grouped. Outliers of different degrees included (1) Tmod4, Myl3 and Myl4 and (2) Myh4, Myot and Actn3. Cluster 1: black dots; Cluster 2: yellow dots; Costamere: blue triangles; Filament: green squares; Z-disk: red dots.