Table 1 The reactions of the model

Zn²⁺-Sensing by ZntR

{Px + Zn ⇄ Px₁, r₁, r₂}

apo-ZntR binding with zinc to become active ZntR

Transcriptional Activation of zntA Gene by

{Dz + Rz ⇄ Qz₁, k_2a, k_-2}

DNA of ZntA binding with RNAP

{Qz₁ ⇄ Dz + Mz + Rz, k₃, 0}

transcription of Qz₁

{Dz + Px ⇄ Qz₄, k_1b, k_-1}

apo-ZntR binding with DNA

{Qz₄+ Rz ⇄ Qz₅, k_2b, k_-2}

apo-ZntR-DNA complex binding with RNAP

{Qz₅ ⇄ Qz₄+ Mz + Rz, k₃, 0}

transcription of Qz₅

{Dz + Px₁ ⇄ Qz₂, k₁, k_-1}

ZnZntR binding with DNA

{Qz₂ + Rz ⇄ Qz₃, k_2c, k_-2}

ZnZntR-DNA complex Binding with RNAP

{Qz₃ ⇄ Qz₂+ Mz + Rz, k₃, 0}

transcription of Qz ₃

Zn²⁺-Sensing by Zur

{Zn²+ Py ⇄ Py₁, r₃, r₄}

Zn₂Zur binding with zinc to become active Zur

Transcriptional Repression of znuC Gene by Zur

{Dw + Py₁ ⇄ Qw₂, k_1a, k_-1}

active Zur binding with DNA to form complex Qw₂ which can not bind with RNAP

{Dw + Rw ⇄ Qw₁, k₂, k_-2}

DNA of ZnuC binding with RNAP

{Qw₁ ⇄ Dw + Mw + Rw, k₃, 0}

transcription of Qw₁

Zn ²⁺ -Binding by TPEN

{Zn + Tp ⇄ Tp₁, r₅, r₆}

TPEN binding with zinc to form a complex