|
D/nm
|
K
M
= 10 μM
|
100 μM
|
1000 μM
|
M (burst size)
|
|---|
|
50
|
67.8
[76.8]
|
67.8
[76.5]
|
67.8
|
1
|
|
100
|
20.8
[26.4]
|
20.6
[26.1]
|
20.6
|
1
|
|
200
|
2.8
|
2.7
|
2.7
|
1
|
|
50
|
1001.8
|
234.9
[169.4]
|
86
|
50
|
|
100
|
343.7
[345.5]
|
73.4
[75.2]
|
26.2
[31.5]
|
50
|
|
200
|
71.4
|
11.3
[11.5]
|
3.6
|
50
|
- The total number of enzyme molecules per compartment is ten in all cases. Values in bold and in square brackets are those estimated by simulation; the italic values are obtained from the theoretical expressions, Eqs. (7) and (12). The parameters are: k0 = 109 s-1 M-1, k1 = k3 = 1000 s-1, k40 = 107 s-1 M-1, and [I] = 10 [ET].
