Global transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3

BMC Systems Biology

Table 4 Reporter-Transcription Factors for the sdh3 Δ mutant

Transcription Factor/Regulator	Number of associated genes	Reporter p-value	Expression p-value	Expression fold change
HAP5	22	1.56E-03	0.262	1.68
HAP4	26	2.27E-03	0.037	-3.36
SLY1	12	3.33E-03	0.341	-1.71
HAP3	25	4.22E-03	0.186	-1.34
SLN1	2	5.71E-03	0.008	-1.91
TRS130	1	1.09E-02	0.015	-1.86
HAP2	28	1.39E-02	0.007	-2.16
FAR1	2	1.47E-02	0.310	-1.32
HYM1	2	1.94E-02	0.148	-1.55
THI2	8	2.30E-02	0.199	1.71
RAP1	26	2.45E-02	0.294	1.97
SWI6	31	2.92E-02	0.289	-1.48
YHP1	1	3.06E-02	0.020	-1.52
YOX1	1	3.06E-02	0.437	1.68
GCR1	18	3.45E-02	0.139	-2.15
THI3	9	3.60E-02	0.514	1.21
CMD1	1	3.87E-02	0.148	2.60

Number of associated genes denotes the genes that are regulated by the corresponding TF/Regulator as documented at the Yeast Proteome Database. Reporter p-value indicates the significance of the average change in the regulated genes. Note that there is no necessary correlation between the reporter p-value and p-value of the expression change in the level of the regulator itself.

ISSN: 1752-0509