Framework of three transcription factor binding sites. The parameters and their abbreviations are: +, sense strand orientation; -, anti-sense strand orientation; cs, minimal core similarity; ms, minimal matrix similarity. Generally, cs was at default (0.75) and ms thresholds were the optimised default values for the respective matrices; distance, number of nucleotides to the next element (arrows in the upper part of the figure). GATA; strand, +; distance to next element, 8–74 bp. MYBL; strand, +; distance to next element, 63–100 bp. MYT1; strand, -.