Figure 3
From: Dynamic simulations on the mitochondrial fatty acid Beta-oxidation network
Simulated acyl-CoA concentrations. Simulated relative concentration of acyl-CoA as a function of carbon chain length for healthy controls (Control) and acyl-CoA dehydrogenase deficiencies (SCADD, MCADD, LCADD, VLCADD). The concentrations of each deficiency are divided by the respective maximum value of concentration. The simulations show accumulation of acyl-CoAs with a maximum at carbon chain lengths of 4 (SCADD), 8 (MCADD), 14 (LCADD) and 16 (VLCAD, Control).