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Table 1 Protein evolutionary rates distribution along the signaling information flow

From: Protein evolution on a human signaling network

Cellular location

Extracellular

Membrane

Cytoplasm

Nucleus

dN/dS (median)

0.220

0.108

0.086

0.094

P value*

1.36 × 10-5

0.01

0.04

0.13

  1. *The P values were calculated by Wilcoxon test by comparing the protein evolutionary rates in each group with the evolutionary rates of the whole network proteins.
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BMC Systems Biology

ISSN: 1752-0509

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