Table 4 List of top ten significant reporter metabolite and subsystem scores for the gdh1/GDH2 vs. wild type comparison in anaerobic conditions.
From: Connecting extracellular metabolomic measurements to intracellular flux states in yeast
Reporter metabolite | Z-score | No of reactions |
|---|---|---|
Glutamate [c] | 4.52 | 35 |
Aspartate [c] | 3.21 | 11 |
Alpha-ketoglutarate [c] | 2.66 | 17 |
Glycine [c] | 2.65 | 7 |
Pyruvate [m] | 2.56 | 7 |
Ribulose-5-phosphate [c] | 2.43 | 4 |
Threonine [c] | 2.28 | 6 |
10-formyltetrahydrofolate [c] | 2.27 | 5 |
Fumarate [c] | 2.27 | 5 |
L-proline [c] | 2.04 | 4 |
Reporter subsystem | Z-score | No of reactions |
Valine, Leucine, and Isoleucine Metabolism | 3.97 | 15 |
Tyrosine, Tryptophan, and Phenylalanine Metabolism | 3.39 | 23 |
Pentose Phosphate Pathway | 3.29 | 11 |
Purine and Pyrimidine Biosynthesis | 3.08 | 40 |
Arginine and Proline Metabolism | 2.96 | 19 |
Threonine and Lysine Metabolism | 2.74 | 14 |
NAD Biosynthesis | 2.66 | 7 |
Alanine and Aspartate Metabolism | 2.65 | 6 |
Histidine Metabolism | 2.24 | 10 |
Cysteine Metabolism | 1.85 | 10 |