Figure 2From: Narrative-based computational modelling of the Gp130/JAK/STAT signalling pathwayRole of inhibitors in the gp130/JAK/STAT pathway. (A) Full model. (B) SOCS3 knock out. (C) PIAS3 knock out. (D) TC-PTP knock out. For each experiment the amounts of different STAT3 forms are plotted: monomeric cytoplasmic (STAT3-C), dimeric cytoplasmic (STAT3-PDC), monomeric nuclear (STAT3-N), and dimeric nuclear (STAT3-PDN).Back to article page