Figure 5

Multi-dimensional parameter sensitivity. The evolution of the system has been observed varying simultaneously the rate of nuclear STAT3 de-phosphorylation and the rate of STAT3 nuclear export. The considered values are as in Figure 4C and 4D. The rows (A-G) refer to the export rate, while the columns (i-v) refer to the de-phosphorylation rate. The amounts of active nuclear STAT3 (STAT3-PDN) and monomeric nuclear STAT3 (STAT3-N) are plotted.