Effect of variation of the miRNA production rate (c
) on the PER protein for Model B. Variation of (a) the frequency and (b) the amplitude of oscillation in the PER protein as a function of c1, the rate of miRNA production. Cases 1 and 2 are shown in blue and red respectively. The other parameters, namely the rate of binding of miRNA to mRNA (c3) and RISC degradation rate (c4) are kept fixed at 0.02 h-1 and 0.001 h-1 respectively.