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Table 2 95%-confidence intervals of the parameters in the reference scenario

From: Mechanism of PP2A-mediated IKKβ dephosphorylation: a systems biological approach

Variable

95%-confidence interval

Unit

ka

[5.0, 8.5]

(μM·s)-1

ki

[0.0025, 0.0042]

s-1

kp

[0.095, 0.095]

s-1

kdp

[0.00060, 0.0011]

s-1

kuv

[0.00016, 0.00032]

s-1

IKKscale

[0.78, 1.2]

-

  1. Confidence intervals were obtained by fitting to perturbed experimental data and determining the 2.5% and 97.5% quantiles of the resulting parameter sets, as described in the Methods section.
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BMC Systems Biology

ISSN: 1752-0509

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