Figure 1

Representative LIPID MAPS pathway in Pathway Editor. The average of 3 lipidomic experiments and one microarray experiment is shown in the default heatmap display format. Shades of red indicate an increase in the ratio of metabolite or gene expression in treated cells with respect to untreated controls measured at the same time point; shades of green represent a reduction in the ratio, or repression of expression. A figure illustrating the alternative line chart display format is shown in [9]. Small molecules are shown as blue rectangular nodes, while protein nodes are shown as green parallelograms (both default shapes for these node types). The default settings for opening a .path file (see text) also feature automated fit to the viewing panel and adjustment of the zoom to the setting contained in the file. View and pathway preferences for any or all nodes and interactions are configurable. The Arachidonic acid metabolism pathway [16] is shown.