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Table 4 P-values of most important H-O and H-D mediators.

From: A quantitative approach to study indirect effects among disease proteins in the human protein interaction network

H-O

protein

avP

H-D

protein

avP

Q5JY77

0.0454

P13500

0.0633

P63104

0.0453

P05129

0.0590

O14908

0.0405

P07948

0.0511

Q14232

0.0356

P22681

0.0370

P17252

0.0345

P09471

0.0342

P28482

0.0328

P63104

0.0282

P49407

0.0305

P80098

0.0271

P06241

0.0269

P80075

0.0234

P62993

0.0244

Q99962

0.0198

P41240

0.0220

Q99616

0.0153

P54646

0.0191

P48745

0.0120

  1. The average P-values (avP) of the most important 11 mediator proteins in the heart-obesity (H-O) and heart-diabetes (H-D) pathways. Note that smaller P-values mean functionally more important proteins.