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Table 4 Summary of the practical identifiability analysis for the successive experimental schemes: a) Predicted maximum uncertainty of the given parameter in %, b) Relative distance between the mean and the nominal value of the parameters in %.

From: An iterative identification procedure for dynamic modeling of biochemical networks

a)

ES 1

  

b)

ES 1

  

c 3a

5.40

  

c 3a

0.02

  

c 4a

9.07

ES 2

ES 3

c 4a

0.66

ES 2

ES 3

c 5

40.8

32.3

16.9

c 5

0.26

0.38

0.6

k 1

20.1

18.0

10.7

k 1

0.46

0.19

0.18

k 2

44.0

14.9

7.85

k 2

1.97

0.51

0.25

k 3

33.7

5.47

 

k 3

0.95

0.10

 

k prod

53.7

23.8

13.2

k prod

2.90

0.42

0.05

k deg

60.8

26.3

15.6

k deg

3.41

0.44

0.03

i 1

16.9

10.4

 

i 1

0.26

0.12

 

i 1a

18.1

8.94

 

i 1a

0.27

0.40

 
  1. Underlined values represent the worst value for the given experimental scheme. Bold face values represent the best value achieved for each parameter at the end of the identification procedure.
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BMC Systems Biology

ISSN: 1752-0509

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