Table 1 Significantly varying products upon EWS-FLI1 oncogene silencing

mRNA_RAS

+

mRNA_ECM1

+

mRNA_RBL2

-

mRNA_CCNE_

+

mRNA_ECM2

+

mRNA_SKP2

+

mRNA_NFKB_

+

mRNA_FAS

-

mRNA_SOS2

+

mRNA_PIK3C_

+

mRNA_FASLG

+

mRNA_TNFAIP3

+

mRNA_PIK3R_

-

mRNA_IER3

+

mRNA_TNFRSF1A

+

mRNA_RAC_

+

mRNA_IGF1

-

Phenotypic_observations

mRNA_RHO_

+

mRNA_IGFBP3

+

mRNA_TGFB_

+

mRNA_JUN

+

EWS-FLI1

-

mRNA_TNF_

+

mRNA_MAPK8

+

Cell_Cycle_Anaphase

-

mRNA_AKT1

+

mRNA_MYC

-

Cell_Cycle_G2

-

mRNA_CDKN1A

+

mRNA_MYCBP

-

Cell_Cycle_M

-

mRNA_CDKN1C

+

mRNA_PDGFRB

+

Cell_Cycle_S

-

mRNA_CYCS

-

mRNA_PRKCB1

-

Cell_Migration

-

mRNA_E2F5

-

mRNA_RASA1

+

Apoptosis

+