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Table 3 13 Modules in gene coexpression network in Figure 2 with their enriched pathways.

From: Integrated analysis of mutations, miRNA and mRNA expression in glioblastoma

Module Module color Pathway category Name P-value
1 Purple Cell signaling Ion channel and phorbal esters signaling 8.60E-03
2 Wind
Apoptosis Apoptotic DNA fragmentation and tissue homeostasis 3.52E-02
   Cell cycle regulation Activation of Src by protein-tyrosine phosphatase alpha 4.23E-02
   Cell cycle regulation AKAP95 role in mitosis and chromosome dynamics 4.98E-02
   Cell cycle regulation Sonic Hedgehog (SHH) Receptor Ptc1 regulates cell cycle 4.23E-02
3 Forest green Translation Ribosome 3.32E-09
4 Teal blue Metabolism of cofactors and vitamins One carbon pool by folate 4.72E-02
5 Black Cell signaling Ca++/Calmodulin-dependent protein kinase Activation 3.59E-03
6 Green
Immunology Cells and molecules involved in local acute inflammatory response 4.68E-02
7 Yellow Cell growth and death Cell cycle 2.62E-02
8 Orange Immunology Classical complement 2.85E-02
9 Lavender Cell signaling IFN alpha signaling 1.03E-02
10 Blue Cell activation Th1/Th2 differentiation 3.79E-02
11 Olive green Metabolism Electron transport reaction in mitochondria 1.31E-02
   Energy metabolism Oxidative phosphorylation 9.00E-03
   Neuro-degenerative diseases Parkinson's disease 8.67E-03
12 Maroon Translation Ribosome 1.13E-03
13 Red Metabolism/Neuroscience Vitamin C in the brain 9.11E-03
   Cell activation Angiotensin-converting enzyme 2 regulates heart function 1.27E-02
   Metabolism Intrinsic prothrombin activation 3.83E-02
   Metabolism Platelet amyloid precursor protein 1.47E-02
   Hematopoiesis Regulators of bone mineralization 2.58E-03