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Table 1 Accuracy of microbial metabolic models vs iMM904 model.

From: Improving the iMM904 S. cerevisiae metabolic model using essentiality and synthetic lethality data

Microorganism

Name of the metabolic model

Specificity (%)

Reference

Saccharomyces cerevisiae

i MM904

38.8

[6] and this study

Escherichiae coli

i AF1260

73.4

[9]

Mycoplasma genitalium

i PS189

79.0

[10]

Bacillus subtilis

i BSU1103

89.3

[11]

Pseudomonas putida

-

74.5

[12]

Helicobacter pylori

i IT341 GSM/GPR

73.0

[13]

Salmonella Typhimurium

i MA945

66.7

[14]

  1. Comparison of the fraction of correctly predicted lethal knockouts (i.e., specificities) of microbial genome-scale metabolic models against the yeast i MM904 model for single gene mutation experiments.