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Archived Comments for: A novel approach to investigate tissue-specific trinucleotide repeat instability

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  1. Note added in proof

    JONG-MIN LEE, Massachusetts General Hospital

    15 April 2010

    While this paper was in revision Goula et al. (PLoS Genet. 2009 December; 5(12): e100074)ublished findings in which they showed that the stoichiometry of base excision repair (BER) roteins differed in striatum compared to cerebellum in an HD fragment mouse odel. It would therefore be of interest to determine whether these findings extend to a roader correlation between tissue instability and BER protein stoichiometry across a wide range of tissues.

    Competing interests

    None declared