Predicted pathways for R. sphaeroides. The known in vitro phosphorylation reactions are shown in the top left. Dotted lines between A1 and R1 and A1 and W1 are assumed, but not experimentally verified, interactions. The predicted pathways for our different models are shown with a green background. Models ABRW+Y and ABRWY+Y give the same prediction. Dotted lines here indicate predicted across-operon PIs. The 3 CheYs shown with no numbers were found by our BLAST searches but are not annotated as CheYs in the literature.