Genome-scale metabolic analysis of Clostridium thermocellum for bioethanol production

BMC Systems Biology

Table 1 Overview of four genome-scale constraint-based models related to ethanol or butanol production.

	C. thermocellum iSR432	C. acetobutylicum[20]	C. acetobutylicum CacMBEL502[21]	S. cerevisiae iND750[3]
Genome size	3.8 Mb	4.1 Mb	4.1 Mb	12.2 Mb
ORFs	3307	4017	4017	6276
Included genes	432	458	432	750
Enzyme complexes	72	n/a^a	36	86
Isozyme cases	70	n/a	n/a	145
Reactions (excluding exchanges)	577	552	502	1150
Transport	73	80	71	308
Gene associated	463	414	431	810
Non-gene associated intracellular	60	119	n/a	123
Non-gene associated transports	54	19	n/a	216
Distinct metabolites	525	488	479	646

ISSN: 1752-0509