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Figure 2 | BMC Systems Biology

Figure 2

From: Discriminating between rival biochemical network models: three approaches to optimal experiment design

Figure 2

Difference between state variables of the two rival models (states of Model 1 minus states of Model 2) in the Initial condition design for model discrimination and Design of structural changes for model discrimination cases. Simulation results for the difference between Models 1 and 2 when started from an arbitrarily perturbed initial condition (0.5774, 0.5774, 0.5774) (a), from the 'best' unit-norm perturbation of the initial condition (1, 0, 0) (b), and with the optimal parameter changes from the corresponding optimally perturbed initial state (1, 0, 0) (c). The corresponding ||y1 - y2||2 values are 0.420, 0.729, and 0.747, respectively.

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