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Table 7 GO term enrichments for central and terminal LCRs.

From: Low-complexity regions within protein sequences have position-dependent roles

Terminal LCRs
Frequencies     
Genes Background p -value q -values GO term ID definition
22 147 1.09 × 10-10 2.76 × 10-08 (P)GO:0006950 response to stress
28 418 3.64 × 10-06 4.62 × 10-04 (P)GO:0006412 translation
6 15 8.55 × 10-06 7.24 × 10-04 (P)GO:0006414 translational elongation
5 10 2.19 × 10-05 0.001 (P)GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation
5 26 8.99 × 10-04 0.046 (P)GO:0006893 Golgi to plasma membrane transport
13 114 1.37 × 10-05 0.002 (F)GO:0016887 ATPase activity
16 202 9.10 × 10-05 0.005 (F)GO:0003735 structural constituent of ribosome
5 33 0.002 0.087 (F)GO:0004175 endopeptidase activity
30 703 0.004 0.087 (F)GO:0000166 nucleotide binding
4 24 0.005 0.087 (F)GO:0005484 SNAP receptor activity
5 40 0.005 0.087 (F)GO:0003743 translation initiation factor activity
3 12 0.006 0.087 (F)GO:0003746 translation elongation factor activity
2 3 0.006 0.087 (F)GO:0019904 protein domain specific binding
7 85 0.008 0.092 (F)GO:0051082 unfolded protein binding
4 28 0.008 0.092 (F)GO:0003688 DNA replication origin binding
2 4 0.009 0.093 (F)GO:0008353 RNA polymerase subunit kinase activity
21 290 2.40 × 10-05 0.003 (C)GO:0005840 ribosome
5 14 7.83 × 10-05 0.006 (C)GO:0015935 small ribosomal subunit
19 284 1.63 × 10-04 0.008 (C)GO:0030529 ribonucleoprotein complex
6 43 0.001 0.038 (C)GO:0043234 protein complex
4 16 0.001 0.038 (C)GO:0000502 proteasome complex
3 9 0.003 0.051 (C)GO:0000786 nucleosome
3 9 0.003 0.051 (C)GO:0000788 nuclear nucleosome
3 9 0.003 0.051 (C)GO:0005852 eukaryotic translation initiation factor 3 complex
6 53 0.003 0.052 (C)GO:0022627 cytosolic small ribosomal subunit
3 10 0.004 0.052 (C)GO:0043614 multi-eIF complex
2 3 0.006 0.065 (C)GO:0034099 luminal surveillance complex
2 3 0.006 0.065 (C)GO:0030133 transport vesicle
2 3 0.006 0.065 (C)GO:0031201 SNARE complex
3 14 0.008 0.082 (C)GO:0005667 transcription factor complex
6 68 0.010 0.096 (C)GO:0030686 90S preribosome
11 189 0.011 0.098 (C)GO:0005730 nucleolus
Central LCRs
Frequencies     
Genes Background p -value q -value GO term ID definition
27 133 3.03 × 10-09 1.40 × 10-06 (P)GO:0006468 protein amino acid phosphorylation
50 518 4.38 × 10-06 0.001 (P)GO:0006350 transcription
45 490 4.52 × 10-05 0.007 (P)GO:0006355 regulation of transcription, DNA-dependent
7 18 9.81 × 10-05 0.011 (P)GO:0006378 mRNA polyadenylation
24 123 4.64 × 10-08 1.03 × 10-05 (F)GO:0004674 protein serine/threonine kinase activity
66 703 2.18 × 10-07 1.68 × 10-05 (F)GO:0000166 nucleotide binding
23 125 2.28 × 10-07 1.68 × 10-05 (F)GO:0004672 protein kinase activity
55 577 1.88 × 10-06 1.04 × 10-04 (F)GO:0005524 ATP binding
15 90 8.39 × 10-05 0.004 (F)GO:0004386 helicase activity
23 204 2.94 × 10-04 0.011 (F)GO:0016301 kinase activity
28 294 8.31 × 10-04 0.026 (F)GO:0003676 nucleic acid binding
10 61 0.001 0.036 (F)GO:0008026 ATP-dependent helicase activity
6 22 0.001 0.036 (F)GO:0004407 histone deacetylase activity
3 4 0.003 0.066 (F)GO:0004708 MAP kinase kinase activity
4 11 0.004 0.077 (F)GO:0005543 phospholipid binding
5 19 0.004 0.077 (F)GO:0016566 specific transcriptional repressor activity
15 63 2.04 × 10-06 3.39 × 10-04 (C)GO:0005934 cellular bud tip
132 1946 4.07 × 10-06 3.39 × 10-04 (C)GO:0005634 nucleus
26 189 5.24 × 10-06 3.39 × 10-04 (C)GO:0005730 nucleolus
5 9 2.89 × 10-04 0.014 (C)GO:0005849 mRNA cleavage factor complex
5 12 7.97 × 10-04 0.031 (C)GO:0000508 Rpd3L complex
16 129 9.96 × 10-04 0.032 (C)GO:0005935 cellular bud neck
  1. GO term enrichments from proteins with c-LCRs and t-LCRs compared to the complete set of proteins in S. cerevisiae.