Table 7 GO term enrichments for central and terminal LCRs.
From: Low-complexity regions within protein sequences have position-dependent roles
Terminal LCRs | |||||
|---|---|---|---|---|---|
Frequencies | |||||
Genes | Background | p -value | q -values | GO term ID | definition |
22 | 147 | 1.09 × 10-10 | 2.76 × 10-08 | (P)GO:0006950 | response to stress |
28 | 418 | 3.64 × 10-06 | 4.62 × 10-04 | (P)GO:0006412 | translation |
6 | 15 | 8.55 × 10-06 | 7.24 × 10-04 | (P)GO:0006414 | translational elongation |
5 | 10 | 2.19 × 10-05 | 0.001 | (P)GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation |
5 | 26 | 8.99 × 10-04 | 0.046 | (P)GO:0006893 | Golgi to plasma membrane transport |
13 | 114 | 1.37 × 10-05 | 0.002 | (F)GO:0016887 | ATPase activity |
16 | 202 | 9.10 × 10-05 | 0.005 | (F)GO:0003735 | structural constituent of ribosome |
5 | 33 | 0.002 | 0.087 | (F)GO:0004175 | endopeptidase activity |
30 | 703 | 0.004 | 0.087 | (F)GO:0000166 | nucleotide binding |
4 | 24 | 0.005 | 0.087 | (F)GO:0005484 | SNAP receptor activity |
5 | 40 | 0.005 | 0.087 | (F)GO:0003743 | translation initiation factor activity |
3 | 12 | 0.006 | 0.087 | (F)GO:0003746 | translation elongation factor activity |
2 | 3 | 0.006 | 0.087 | (F)GO:0019904 | protein domain specific binding |
7 | 85 | 0.008 | 0.092 | (F)GO:0051082 | unfolded protein binding |
4 | 28 | 0.008 | 0.092 | (F)GO:0003688 | DNA replication origin binding |
2 | 4 | 0.009 | 0.093 | (F)GO:0008353 | RNA polymerase subunit kinase activity |
21 | 290 | 2.40 × 10-05 | 0.003 | (C)GO:0005840 | ribosome |
5 | 14 | 7.83 × 10-05 | 0.006 | (C)GO:0015935 | small ribosomal subunit |
19 | 284 | 1.63 × 10-04 | 0.008 | (C)GO:0030529 | ribonucleoprotein complex |
6 | 43 | 0.001 | 0.038 | (C)GO:0043234 | protein complex |
4 | 16 | 0.001 | 0.038 | (C)GO:0000502 | proteasome complex |
3 | 9 | 0.003 | 0.051 | (C)GO:0000786 | nucleosome |
3 | 9 | 0.003 | 0.051 | (C)GO:0000788 | nuclear nucleosome |
3 | 9 | 0.003 | 0.051 | (C)GO:0005852 | eukaryotic translation initiation factor 3 complex |
6 | 53 | 0.003 | 0.052 | (C)GO:0022627 | cytosolic small ribosomal subunit |
3 | 10 | 0.004 | 0.052 | (C)GO:0043614 | multi-eIF complex |
2 | 3 | 0.006 | 0.065 | (C)GO:0034099 | luminal surveillance complex |
2 | 3 | 0.006 | 0.065 | (C)GO:0030133 | transport vesicle |
2 | 3 | 0.006 | 0.065 | (C)GO:0031201 | SNARE complex |
3 | 14 | 0.008 | 0.082 | (C)GO:0005667 | transcription factor complex |
6 | 68 | 0.010 | 0.096 | (C)GO:0030686 | 90S preribosome |
11 | 189 | 0.011 | 0.098 | (C)GO:0005730 | nucleolus |
Central LCRs | |||||
Frequencies | |||||
Genes | Background | p -value | q -value | GO term ID | definition |
27 | 133 | 3.03 × 10-09 | 1.40 × 10-06 | (P)GO:0006468 | protein amino acid phosphorylation |
50 | 518 | 4.38 × 10-06 | 0.001 | (P)GO:0006350 | transcription |
45 | 490 | 4.52 × 10-05 | 0.007 | (P)GO:0006355 | regulation of transcription, DNA-dependent |
7 | 18 | 9.81 × 10-05 | 0.011 | (P)GO:0006378 | mRNA polyadenylation |
24 | 123 | 4.64 × 10-08 | 1.03 × 10-05 | (F)GO:0004674 | protein serine/threonine kinase activity |
66 | 703 | 2.18 × 10-07 | 1.68 × 10-05 | (F)GO:0000166 | nucleotide binding |
23 | 125 | 2.28 × 10-07 | 1.68 × 10-05 | (F)GO:0004672 | protein kinase activity |
55 | 577 | 1.88 × 10-06 | 1.04 × 10-04 | (F)GO:0005524 | ATP binding |
15 | 90 | 8.39 × 10-05 | 0.004 | (F)GO:0004386 | helicase activity |
23 | 204 | 2.94 × 10-04 | 0.011 | (F)GO:0016301 | kinase activity |
28 | 294 | 8.31 × 10-04 | 0.026 | (F)GO:0003676 | nucleic acid binding |
10 | 61 | 0.001 | 0.036 | (F)GO:0008026 | ATP-dependent helicase activity |
6 | 22 | 0.001 | 0.036 | (F)GO:0004407 | histone deacetylase activity |
3 | 4 | 0.003 | 0.066 | (F)GO:0004708 | MAP kinase kinase activity |
4 | 11 | 0.004 | 0.077 | (F)GO:0005543 | phospholipid binding |
5 | 19 | 0.004 | 0.077 | (F)GO:0016566 | specific transcriptional repressor activity |
15 | 63 | 2.04 × 10-06 | 3.39 × 10-04 | (C)GO:0005934 | cellular bud tip |
132 | 1946 | 4.07 × 10-06 | 3.39 × 10-04 | (C)GO:0005634 | nucleus |
26 | 189 | 5.24 × 10-06 | 3.39 × 10-04 | (C)GO:0005730 | nucleolus |
5 | 9 | 2.89 × 10-04 | 0.014 | (C)GO:0005849 | mRNA cleavage factor complex |
5 | 12 | 7.97 × 10-04 | 0.031 | (C)GO:0000508 | Rpd3L complex |
16 | 129 | 9.96 × 10-04 | 0.032 | (C)GO:0005935 | cellular bud neck |