OptORF: Optimal metabolic and regulatory perturbations for metabolic engineering of microbial strains

BMC Systems Biology

Table 2 Gene deletion strategies for ethanol production in E. coli

The predicted ethanol yields and growth rates are listed for two-deletion strategies and five-deletion strategies. Three or four deletion strategies are not shown because the ethanol yield was not significantly improved over two deletion strategies. The variability in ethanol yield at the predicted maximum growth rate was zero or very small (< 0.01%) for all cases. The ethanol yield is reported as % of the maximum theoretical yield (100% is 0.51 g ethanol/g glucose or 2 mol ethanol/mol glucose). Maximum glucose uptake rate of 18.5 mmol/gDW/hr was used to simulate anaerobic growth conditions.

ISSN: 1752-0509