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Table 2 Partial flux control coefficients for glucose-6-phosphate isomerase (r2)

From: Dynamics and Control of the Central Carbon Metabolism in Hepatoma Cells

  Partial flux control coefficient through  
Enzyme G6Pin F6Pin 6PGin Flux control coefficient
r1 5.64 -2.31 -3.18 0.15
r2 -0.61 -0.52 0.24 0.11
r3 -0.34 0.33 0.14 0.13
r4 -0.44 0.42 0.18 0.16
r5 -0.06 0.06 0.02 0.02
r6 -1.11 0.74 0.76 0.38
r7 -0.02 0.01 0.01 0.01
r8 -0.06 0.03 0.04 0.02
r9 0.00 0.00 0.00 0.00
r10 6.68 4.09 -12.40 -1.63
r11 0.30 0.19 -0.56 -0.07
r12 -3.12 -2.86 6.49 0.50
r13 0.19 -0.21 -0.05 -0.07
r14 -5.06 -2.90 8.98 1.02
r15 1.16 -1.20 -0.40 -0.44
r16 -1.91 1.62 0.97 0.69
r17 0.00 0.00 0.00 0.00
r18 -2.24 1.85 1.20 0.81
r19 -1.42 -0.03 1.12 -0.33
r20 0.02 -0.01 -0.02 -0.01
r21 0.00 0.00 0.00 0.00
r22 0.78 1.37 -2.69 -0.54
r23 -0.02 0.01 0.01 0.00
r24 0.10 -0.10 -0.03 -0.04
r25 -0.04 -0.01 0.06 0.01
r26 -0.01 0.00 0.00 0.00
r27 -0.05 0.00 0.06 0.01
r28 0.04 -0.02 -0.03 -0.01
r29 0.62 -0.39 -0.42 -0.20
r30 -0.08 0.09 0.02 0.03
r31 -0.14 0.17 0.03 0.06
r32 -0.08 0.10 0.02 0.04
r33 -0.02 0.06 -0.02 0.02
r34 -0.02 0.05 -0.02 0.02
r35 0.18 -0.11 -0.12 -0.06
r36 2.15 -1.36 -1.46 -0.67
r37 -0.01 0.01 0.00 0.00
r38 -0.10 0.05 0.08 0.03
r39 0.17 -0.32 0.05 -0.09
r40 -0.03 0.09 -0.03 0.03
r41 -4.38 2.55 3.32 1.48
r42 0.37 -0.42 -0.10 -0.15
r43 -0.45 0.57 0.09 0.21
r44 0.09 -0.13 0.00 -0.04
r45 -0.05 0.04 0.03 0.02
r46 1.82 -0.94 -1.40 -0.53
r47 1.24 -0.51 -0.70 0.03
r48 0.12 -0.05 -0.11 -0.03
r49 0.18 -0.10 -0.14 -0.06
  1. Partial flux control coefficients are only shown for metabolites that have an effect on the glucose-6-phosphate isomerase (r2), i.e. that have non-zero elasticities. The sum of the partial flux control coefficients over all intermediates equals the flux control coefficient. With regard to the control of an enzyme over its own flux, the flux control coefficient equals the sum of the partial flux control coefficients plus one.