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Figure 1 | BMC Systems Biology

Figure 1

From: Reconstruction of the yeast protein-protein interaction network involved in nutrient sensing and global metabolic regulation

Figure 1

The process of the reconstruction of the key signal transduction pathways embedded in the global protein-protein interaction network of S. cerevisiae. From different types of available information such as different biochemical pathway databases, different textbooks, recent publications and reviews and genome annotations, a physical reconstruction of a protein-protein interaction network was designed and annotated so that each protein and their interactions include all information. The pathway map picture was taken from the KEGG database ( and SGD, Biogrid, Cytoscape and CellDesigner logos were taken from their respective websites.

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